Saturday, April 16, 2011

March 20th, 2011

Just on update on values:

A1c in January 10th, 2011, was 7.3% (from 6.8% last). Let's add that this was after a huge vacation feasting on junk food.

So after we went back to normal meals, A1c in March 20th, 2011 was 6.3%. No big restrictions, just normal meals at home, eyeballing the corrections.

NPH is at a total of 67 units for the day, 5 units for the night. Age is 12, weight is 50kg (110 lbs), height 1.50 mtrs (59 inches). That's about 1.5 Units per kgrm.

I'm sure those following the blog knew that in August 2010 Lilly and Macrogenics announced the suspension of the trials because the low efficacy of the drug. They also added that there were not unanticipated safety issues.

As someone put it, results were not terrific in the vast majority of the patients. Unfortunately, so far results for the star patients were not released, neither a paper with the results of this particular trial.

There's now another trial ( http://clinicaltrials.gov/ct2/show/NCT01030861 ) to see if the drug is able to prevent or delay the onset of diabetes in relatives at risk. I'm glad to hear that, because if there were safety issues -yes, I know, they've said there were none unanticipated-, I think we would not see another trial.

I'll keep posting A1c every 3 months and any dramatic change in anything, for example diet.

If you look at all the previous posts, diet has been from lousy to normal all this time, which is great, as the boy can go to a birthday party (with a preload of insulin), and eat the same as everyone else's. The only precaution is to take diet sodas.

So long folks!